Structural distinctions in BMPs underlie divergent signaling in spinal neurons
Abstract Background In dorsal spinal neurons and monocytes, bone morphogenetic protein (BMP)7 activates distinct transduction pathways, one leading to inductive specification and the other to read more axon orientation and chemotaxis.BMP7-evoked induction, also stimulated by the closely related BMP6, acts through a Smad cascade, leading to nuclear